Which treatment should I choose, Wegovy or Mounjaro uk ?

Which treatment should I choose, Wegovy or Mounjaro uk ? Wegovy and Mounjaro are both weekly injection pens and work in similar ways to aid weight loss. Mounjaro has proven more effective in clinical trials, as it works on GLP-1 and GIP hormones, whereas Wegovy only works on GLP-1. However, Mounjaro is a new medicine in the UK so we don’t have as much safety data on it compared to other medicines in the long term. Deciding if or which medicine is right for you will depend on different factors, which we’ll assess during your consultation. If you’re already on Wegovy (or Saxenda) and losing weight, we recommend you keep using it. Keep in mind, weight plateaus are normal on your weight loss journey.

Does Mounjaro come with swabs?

The ‘instructions for use’ that come with the pen advise that you use swabs – you can purchase these in your Boots store when you collect your pen, or online.

Is mental health support available for weight loss patients?

Packages

This treatment is available as:

Mounjaro 2.5mg

1 Pen

£176.97

Mounjaro 5mg

1 Pen

£189.97

Mounjaro 7.5mg

1 Pen

£267.97

Mounjaro 10mg

1 Pen

£302.97

Mounjaro 12.5mg

1 Pen

£314.97

Mounjaro 15mg

1 Pen

£334.97

Service Led By And Approved By:

Dr Anju Verma

GMC no. 6039302

Dr Anju is Clinical Lead for the Weight Loss service and Menopause Advisor. She is SCOPE certified (international gold standard for obesity management) and has a wealth of expertise across clinical medicine, general practice and digital healthcare.

No appointment needed

Health shouldn’t have to wait. It shouldn’t have to depend on appointment availability. You deserve access to quality treatment and support whenever you need it. Looking to replace your asthma inhaler or stave off hayfever? Need help to stop smoking or with managing your migraines? We’ve got you covered.

Boots Digital Health Ltd is registered with the Care Quality Commission and provides the Boots Online Doctor Service.

Choosing between Wegovy and Mounjaro requires a consultation with a healthcare professional to determine the best option for your specific health profile, medical history, and goals. Mounjaro generally leads to greater average weight loss, while Wegovy has more established long-term safety data and a proven benefit for cardiovascular risk reduction.

Key Differences at a Glance

Feature	Wegovy (Semaglutide)	Mounjaro (Tirzepatide)
Primary Approval	Weight management and cardiovascular risk reduction	Type 2 diabetes treatment
Mechanism	GLP-1 receptor agonist (single action)	Dual GLP-1 and GIP receptor agonist (dual action)
Average Weight Loss	~15-17% of body weight in clinical trials	~20-22.5% of body weight in clinical trials
Cardiovascular Benefit	Proven to reduce risk of heart attack/stroke	Still being studied for this benefit
NHS/Insurance Access	More widely available on the NHS (UK) and covered by some insurers for weight loss	NHS access is limited; private prescription only in many cases
Cost	Generally less expensive privately (UK pricing)	Generally more expensive privately (UK pricing)
Side Effects	Similar gastrointestinal issues; potentially slightly fewer side effects in some studies	Similar gastrointestinal issues; side effects may be more intense initially

Considerations for Choosing

Weight Loss Goals: If achieving the maximum possible average weight loss is the primary goal, Mounjaro’s dual-action mechanism may offer superior results.
Existing Health Conditions: Mounjaro provides excellent blood sugar control and may be a better option if you also have Type 2 diabetes. Wegovy is specifically approved to lower the risk of major adverse cardiovascular events in people with obesity or who are overweight with risk factors.
Cost and Availability: Insurance coverage varies greatly. In the UK, Wegovy has more established pathways for NHS access for eligible patients, whereas Mounjaro is often only available via private prescription, which can be costly.
Side Effect Tolerance: Both medications share similar common side effects (nausea, diarrhea, constipation). Individual tolerance varies, and some people may find one medication more manageable than the other.
Contraception: Mounjaro can reduce the effectiveness of oral contraceptives, requiring the use of alternative barrier methods. Wegovy does not have this interaction.

Ultimately, the “best” treatment is the one that is safe and most suitable for your unique needs and lifestyle after a full medical assessment. Always consult a qualified healthcare professional before starting any weight loss medication.

Get care wherever you are

Convenient, discreet treatment

Experienced clinicians

No appointment needed